A trans man is taking testosterone and has undergone a mastectomy and hysterectomy. What is this patient most at risk for?

The patient in question has transitioned from female to male, utilizing testosterone therapy and undergoing both a mastectomy and hysterectomy. One of the physiological effects of testosterone, particularly in individuals who transition and undergo surgical procedures, is an altered cardiovascular profile.

Testosterone therapy may lead to changes in lipid levels, increases in red blood cell mass, and potential elevations in blood pressure, all of which contribute to an increased risk of cardiovascular diseases. This is especially pertinent in trans men, as they may face additional cardiovascular risks compared to the general population due to these hormonal changes and potential pre-existing health factors.

While other options like cancer could be a concern (particularly if considering the risk for cancers related to hormonal changes), the direct and immediate risk tied to testosterone usage and the physiological changes it affects is primarily related to cardiovascular health. Monitoring cardiovascular status in individuals undergoing hormone therapy is essential to ensure proper management of any emerging risks.

In summary, the combination of testosterone therapy and the background of transitioning leads to heightened awareness of cardiovascular disease risks, making it the most relevant concern for this patient.